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Understanding
skin ageing
Cellular Science

Skin ageing

With age, skin gradually loses key structural components

The skin is the body’ largest organ and acts as a protective barrier from the external environment. It has a complex structure containing multiple layers, structural proteins and other vital components responsible for its healthy appearance and normal functionning.

Skin ageing is a natural process. It is affected by internal factors such as genetics and external factors including UV damage, smoking, alcohol and poor diet, environmental pollution and stress.

With age, skin gradually loses key structural components like collagen, elastin, silicium and moisture retaining compounds called ceramides and hyaluronic acid and as a result the skin becomes less smooth, full and elastic.

Oxidative stress and skin ageing

Oxidative stress is the body’s inability to neutralize destructive radicals

The ability to deal with damaging free radicals, produced as a result of internal and external aggressions, also declines with age. Free radicals are unstable molecules that damage skin cells in the oxidative stress process and unless quenched can accumulate, leading to oxidative stress and premature ageing from lines to wrinkles and dullness, uneven tone and loss of firmness.

Oxidative stress is defined as an over production of destructive radicals, the most commonly known as Reactive Oxygen Species (ROS), and an inability of the body’s natural antioxidant network to neutralize them before they do damage to skin by further breaking down collagen and elastin with the consequent loss of the skin’s support structure.

Avoiding the effects causes of free radicals and adopting a lifestyle that helps fight back against them can help safeguard healthy skin but with age this often is oftentimes not enough to prevent oxidative stress. This is when antioxidant supplementation is needed.

A unique Swiss patent formulation that unlocks beauty from within

Collagen

By the age of 50, we have naturally lost almost 50% of the collagen from our skin

Collagen is the most abundant structural protein in the human body forming the main structural element of the skin and responsible for the collagen cohesion, elasticity and regeneration.

By the age of 50 we have naturally lost almost 50% of the collagen from our skin. As a result, skin becomes fragile, less elastic, loses its capacity to maintain hydration and wrinkles begin to appear. This is when supplemental forms of collagen should be added to your daily regime.

Supplementing collagen to the skin is best achieved by a specific form called hydrolyzed collagen which is comprised of small amino acids, the so called collagen peptides, which are absorbed quickly by the body and stimulate the body’s own natural production of collagen. In clinical studies, this bioavailable form of collagen has shown to significantly reduce wrinkle depth, increase elasticity and skin hydration levels.

Ceramides

Ceramides are responsible for the barrier and moisture retention functions of the skin

Skin epidermis is constituted of cells looking like « bricks ». Ceramide, another major component of the skin, is the key constituent of the cement between these bricks and is responsible for the barrier and moisture retention functions of the skin. In addition to its function as protection against moisture loss, ceramides help fight against oxidative stress by forming a skin barrier and thus help to promote a youthful appearance. Ceramide content naturally decrease with age and during winter.

Where there are is not enough ceramides, water is lost through the epidermis resulting in skin dryness and ageing.

Phytoceramides such as those found in SKIN BEAUTY COMPLEX by Collagen Reverse are shown to significantly replenish and restore what age takes away, contributing to a healthy, youthful glow.

Hyaluronic acid

Hyaluronic acid helps retain collagen and increase moisture, contributing to skin’s suppleness, hydration and elasticity

Hyaluronic acid is an important natural component of skin produced by fibroblasts (cells in connective tissues which produce collagen). It helps retain collagen and increase moisture, contributing to skin’s suppleness, hydration and elasticity. As we age, the natural production of hyaluronic acid decreases and our skin loses the ability to preserve moisture. As a result, the skin becomes dehydrated, the collagen and elastin fibers lose their structure, resulting in loss of skin volume and the formation of the facial wrinkles and folds that are common characteristics of aged skin.

The good news is that by supplementing the diet with hyaluronic acid, the skin is hydrated, looks more plump and healthy.

Silica

Silica has essential functions for the stimulation of collagen and elastin production

Silica is a key structural element of connective tissue and has an important role for the good functioning of the cell membranes. Together with vitamin C, silica stimulates the natural collagen and elastin formation in the human skin.

The elastin capital is produced in adolescence and then decreases with time. As we age, elastin is replaced by collagen which is inextensible, resulting in loose skin and the appearance of wrinkles. Silicium is opposed to elastase which degrades elastin and helps preserve the elastin in the body longer.

The biovailability of silica is also affected by ageing and the decline of oestrogenic permeation and increased need for a bioavailable supplement of silica is needed.

Due to its essential functions for the collagen and elastin production, silicium has an important role to play in ensuring skin firmness, texture and smoothness and a bioavailable supplemental form as found in SKIN BEAUTY COMPLEX by Collagen Reverse is needed to replenish the loss we experience with age.

PRIMARY ANTIOXIDANTS

The primary antioxidant in SKIN BEAUTY COMPLEX by Collagen Reverse is able to control and prevent the development of oxidative stress


As we have seen, oxidative stress may result in significant damage to cell structures, contributing to premature skin ageing, if not eliminated.
Studies have shown that SOD B, a melon extract highly concentrated in natural and bioactive SuperOxide Dismutase, is able to control and prevent the development of oxidative stress from the starting point of cellular oxidation. With its capacity to constantly renew ifself, this primary antioxidant is proven to provide the best and continued protection for the skin against daily oxidative attacks.

SKIN BEAUTY COMPLEX by Collagen Reverse has SOD B Primo Antioxidant® that is scientifically proven to provide this unique protection thanks to its precursor activity against the source of all oxidative damages in the body.

SECONDARY ANTIOXIDANTS

Secondary antioxidants do not have the capacity to prevent and defend the formation of free radicals at its early stage

Operating further on the oxidative stress mechanism, vitamin C and E, zinc and polyphenols are part of the socalled secondary antioxidants. Only externally provided from dietary sources, those molecules do not have the capacity to prevent and defend the formation of free radicals in its early stage. Being common secondary antioxidants, these show a radically different mode of action with a faster onset of action, providing a boosting effect that will not be offered by SOD B.

Showing complementary effects; SOD B, vitamin C and E, zinc and polyphenols combined, provide synergistic effects, contribute to optimal correction of oxidative stress and offer skin health benefits.

The secret to fight skin ageing and to a radiant complexion is to unlock the formula of active ingredients that supply our bodies with what is needed to naturally revive the skin from within. This is when SKIN BEAUTY COMPLEX by Collagen Reverse comes in.

Collagen Reverse - Skin Beauty Complex - Pack 14

CELLULAR SCIENCE

Our Swiss team behind SKIN BEAUTY COMPLEX by Collagen Reverse have developed a 4D approach to skin health, using the highest quality hydrolyzed marine collagen to strengthen the skin structure, ceramides, hyaluronic acid and silicium in addition to primary and secondary antioxidants that synergistically nourish, reconstruct and protect the skin from internal and external agressions.

Composition complément alimentaire

Peptan® hydrolyzed marine collagen Hyaluronic acid Silicium

Slow the loss of collagen while simultaneously stimulating the cell dermis for natural collagen production and protecting against elastin degradation. Shown to reduce wrinkle depth, increase elasticity and boost the skin hydration level.

CeramocidesTM Phyto ceramides

Supports skin cellular matrix, contributing to increased firmness and hydration. Clinically proven to help improve skin elasticity and the appearance of wrinkles.

Vitamin C & E Zinc Vitis vinifiera / Red grape extract

Together support collagen synthesis and the cell division process combined with protection against membrane degradation and oxidative stress. Actions that can be related directly to the prevention of premature skin aging.

Primo antioxydant® SOD B

Removes free radicals and prevents the development of oxidative stress. Scientifically demonstrated to inhibit both cell oxidation and inflammation for better prevention of cell aging.

CLINICAL STUDIES

All key ingredients in SKIN BEAUTY COMPLEX by Collagen Reverse have demonstrated efficacy
on skin in human clinical studies.

MARINE COLLAGEN PEPTIDES PEPTAN® CLINICAL STUDIES

RESTRUCTURE COLLAGEN
A randomized, placebo-controlled double-blind clinical trial showed an improvement in the skin’s collagen structure and density after 12 weeks of Peptan intake.

INCREASE SKIN HYDRATION
A randomized, placebo-controlled double-blind clinical trial showed after 8 weeks of Peptan intake, the skin hydration level is higher.

CERAMOSIDES™ CLINICAL STUDIES

Increase skin elasticity

Reduce wrinkle depth

8 out of 10 volunteers involved in the studies felt an improved skin appearance after taking ceramosides™ for 2 months

Without ceramocides

Moisture evaporates from the skin

With ceramocides

Ceramosides create barrier to keep moisture in

SOD B PRIMO ANTIOXIDANT® CLINICAL STUDY

sod-b-etude-clinique-collagen-reverse

Boost antioxidant defenses

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